Provide central direction, leadership and coordination of scientific and technological efforts and ensure that the results therefrom are geared and utilized in areas of maximum economic and social benefits for the people.
- Forests Product Research and Development Institute (FPRDI)
- Industrial Technology Development Institute (ITDI)
- Philippine Council for Agriculture, Aquatic and Natural Resources Research and Development (PCAARRD)
- Philippine Council for Industry, Energy and Emerging Technology Research and Development (PCIEERD)
- Philippine Council for Health Research and Development (PCHRD)
- National Research Council of the Philippines (NRCP)